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LIM KINASES
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DeCS
Descriptor
English
:
Lim Kinases
Descriptor
Spanish
:
Quinasas Lim
Descriptor
Portuguese
:
Quinases Lim
Tree Number:
D08.811.913.696.620.682.700.542
D12.644.360.390
D12.776.476.396
D12.776.512.124
Definition
English
:
Serine
protein kinases
involved in the regulation of ACTIN
polymerization
and MICROTUBULE disassembly. Their activity is regulated by
phosphorylation
of a
threonine
residue within the activation loop by intracellular signaling kinases such as
P21-ACTIVATED KINASES
and by RHO KINASE.
History Note
English
:
2008
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
52744
Unique Identifier:
D054461
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS